SelectSIEVE® Apple PCQ 2018-02-01T18:39:21+00:00

Project Description

SelectSIEVE® Apple PCQ

The super fruit to modulate glycaemia

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Ingredient benefits

SelectSIEVE®Apple PCQ is composed of functional polyphenols, which act in a complementary manner through different metabolic pathways.

What is it?

SelectSIEVE®Apple PCQ is an active ingredient based on balanced and highly standardized polyphenols from apple.

What does it do?

SelectSIEVE®Apple PCQ components are reported to modulate glucose up-take and metabolism into the body.
They also positively influence the endothelial reactivity favoring a better blood flow and contribute to prevent CVD by bad cholesterol reduction.
These activities are useful for hyperglycemia prevention, carbohydrates in-take modulation and cardiovascular health.

Biological target

People affected by hyperglycemia or subjected to high risk of cardiovascular disease due to overweight.

Mechanism of action

  • Reduction of calories intake through competitive inhibition of intestinal glucose absorption due to the Phloridzinbond to the SGLT1/GLUT transporters
  • Regulation of hepatic glycaemia through modulation of the G6P-translocase activity by chlorogenicacid
  • Increase of draining through the improvement of blood circulation due to vasculoprotectorand veinotonicaction of flavonoids
  • Limitation of fat storage due to the repression of the PPAR-γ gene (differentiation of pre-adipocytes into mature adipocytes) then reducing fat storage
  • Metabolic effect by improving the endothelial reactivity and reducing the serum uric acid



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